From the depths of the Indian Ocean, a horrific plague has arisen to devastate humankind. But it is merely a harbinger of the doom that is to follow. Aboard a cruise liner transformed into a makeshift hospital, Dr. Lisa Cummings and Monk Kokkalis, operatives of SIGMA Force, search for answers to the bizarre affliction. But there are others with far less altruistic intentions. In a savage and sudden coup, terrorists hijack the vessel, turning a mercy...

After a mountainside massacre yields a grim message, Painter Crowe, director of Sigma Force, must join with Commander Grayson Pierce and an unlikely ally if he is going to get to the root of a conspiracy that stretches back to a lost prehistoric colony in America.